- Agriculture
- Antibiotic/anti-viral
- Biologics
- Biomarkers
-
By Clinical Application
- Anesthesiology
- Blood & Lymphatic Disease
- CNS & Neurosciences
- Dermatology
- Diabetes, Metabolism, Endocrinology & Obesity x
- Ear, Nose, & Throat
- Emergency Services
- Gastroenterology & Digestive Disease
- General & Plastic Surgery
- Health Education, Medical Training and Operations
- Heart and Vascular
- Immunology, Autoimmune & Inflammation
- Infectious Diseases
- Mental Health
- Multiple clinical applications
- Musculoskeletal Disorders, Orthopedics/Bone
- Nephrology/Renal
- Oncology
- Ophthalmology
- Orphan Diseases
- Pediatrics
- Physical Medicine & Rehabilitation
- Radiology
- Regenerative Medicine / Tissue Engineering
- Reproductive Health: Obstetrics & Gynecology
- Respiratory & Pulmonary
- Surgery
- Transplantation
- Urology
- Wound Healing
- COVID-19
- Creative Works
- Diagnostics
- Drug Delivery
- Drug screening and discovery
- Energy, Cleantech & Environmental
- Engineering & Physical Sciences
- Gene therapy
- Imaging
- Materials
- Medical Devices
- Nutraceuticals
- Other
- Research & Design Tools
- RNAi/siRNA
- Sensors & Controls
- Small molecules
- Software & Information Technology
- Stem Cells
- Vaccines
- Veterinary Medicine
Dual agonist proteins for the treatment of type 2 diabetes
Unmet Need Over 37 million people in the United States have diabetes, and approximately 90-95% of them have type 2 diabetes (T2D). Diabetes and its related complications not only cause premature mortality and lower quality…
A method to optimize neural activity blocking therapies
Unmet Need The use of kilohertz frequency (KHF) as neuromodulatory therapies that block unwanted neural activity have been applied to treat chronic pain, phantom limb pain, obesity, and other applications. However, the high energy demands…
The Trail Guide curriculum for childhood obesity treatment program model
Unmet Need Childhood obesity is an ongoing health concern involving cardiometabolic risk, reduced quality of life and long-term health consequences. Current child obesity treatment guidelines recommend 26 or more hours of behavior treatment, delivered over…
A method of screening and monitoring glycogen storage diseases with a single biomarker
Unmet Need Glycogen storage disease type I (GSD I) is an autosomal recessive inherited disorder of carbohydrate metabolism associated with life threatening fasting hypoglycemia, and significant morbidity and mortality. Currently, the standard of care therapy…
A target for identifying and treating metabolic diseases including insulin resistance
Unmet Need The World Health Organization attributes over 70% of all deaths globally to noncommunicable diseases (NCD) including cardiovascular disease, diabetes, and cancer. Risk factors for NCDs include obesity, raised blood pressure, and the regional…
An algorithm for tracking nutrition that can accurately categorize foods based on image
Unmet Need Obesity prevalence for adults in the United States has reached 42.4% according to the most recent report from the National Center for Health Statistics. Given the public health and medical consequences of obesity…
Method for treating glycogen storage disease
The present disclosure is directed to methods of treating a cytoplasmic glycogen storage disorder, including glycogen storage disease I, glycogen storage disease III, glycogen storage disease IV, and/or conditions associated with a PRKAG2 mutation, by…
A drug combination that reduces weight gain associated with antidepressant therapy
Newer generation antidepressants seem less likely to be associated with cardiovascular side effects and toxicity associated with older generation antidepressants, such as tricyclic antidepressants or monoamine oxidase inhibitors (MAOIs). Currently, newer generation antidepressants include selective…
The combination of bupropion (Wellbutrin, Wellbutrin-SR, Zyban) and zonisamide (Zonegran) can be an effective weight loss and weight maintenance treatment for obese patients.
Technology The present invention relates, in general, to obesity, and, in particular, to a method of treating obesity and minimizing metabolic risk factors associated therewith using, for example, zonisamide or other weight-loss promoting anticonvulsant either…
A peptide therapy for diabetes that improves islet cell mass and function
Methods of modulating blood glucose levels treating hyperglycemia and related complications and conditions by administration of a VGF biomolecule to a patient in need of such treatment are provided. Methods of enhancing insulin secretion from…
A novel signaling pathway regulating food intake and energy metabolism
Detailed knowledge of the pathways by which gherlin and leptin signal to AMPK in hypothalamic neurons and lead to regulation of appetite and glucose homeostasis is central to the development of effective means to combat…