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Structural variants of TERT in brain tumors

Structural variants of TERT in brain tumors

Unmet Need Glioblastoma is the most common type of malignant brain tumor, and accounts for 47.7% of all brain cancer cases. Despite aggressive treatment, the median overall survival for glioblastoma is 15 to 18 months.…

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Predicting immune checkpoint therapy for breast cancer patients using LRRK2 mutations

Predicting immune checkpoint therapy for breast cancer patients using LRRK2 mutations

Unmet Need The treatment of various cancers has been revolutionized by the development of effective immunotherapies that are now established as powerful clinical tools. Unfortunately, it is also now well documented that only a minority…

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