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A humanized pro-N-cadherin antibody that can be used for treating and predicting heart failure

A humanized pro-N-cadherin antibody that can be used for treating and predicting heart failure

Unmet Need Heart failure is the leading cause of morbidity and mortality in the developed world. Approximately 50% of the US population over the age of 45 is expected to have preclinical heart failure, and…

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Aptamer anticoagulant therapy to reduce complications of ECMO treatment

Aptamer anticoagulant therapy to reduce complications of ECMO treatment

Unmet Need Extracorporeal membrane oxygenation (ECMO) is a life-saving treatment for critically ill patients with low oxygen levels. During ECMO, the patient’s blood flows through an external oxygenation device. This requires co-treatment with an anticoagulant…

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Novel AnnexinA1 tripeptide (ANXA1sp) improves acute kidney injury after deep hypothermic circulatory arrest

Novel AnnexinA1 tripeptide (ANXA1sp) improves acute kidney injury after deep hypothermic circulatory arrest

Value Proposition Heart disease is the leading cause of death in industrialized nations across the world, with treatments often requiring surgery such as coronary artery bypass graft (CABG) or even transplantation. Although cardiac surgery is…

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