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Methods to modify plant stress responses and enhance expression of target proteins
Unmet Need There are over 8 billion people on our planet today that rely on several crops, including rice, corn, and wheat, as a primary source of sustenance. However, global climate change and the increased…
Polymer dendrimers as potent and selective inhibitors of bacterial crop diseases
Unmet Need Currently, the agriculture industry relies on broad-spectrum antibiotics to ensure high crop yields, but farmers still suffer losses of 17-30% to disease and blight. Furthermore, the use of broad-spectrum antibiotics to treat these…
A protein that promotes crop immunity without compromising growth
Unmet Need The human population is growing, and more food will be needed to sustain the global community, with an expected increase in total global food demand of 35% to 56% in the next 25…
Novel regulators of root growth
Value Proposition With growing populations and changing climate, agricultural technologies that enhance crop growth and increase stress tolerance are crucial. Stress tolerance, which includes low soil fertility and drought conditions, are relevant to both crop…
A technique that promotes the stringent control of gene expression within specific cell types
Unmet Need A major challenge of gene therapy is to target only the intended cell- and/or tissue-type. For this reason, many gene therapies are delivered using adeno-associated virus (AAV) vectors with gene-specific promoters; however, off-target…
A method for identifying sour-taste receptor ligands as well as compounds that modulate their activity
Unmet Need The taste system is essential for feeding and survival as it helps humans evaluate the nutritional content in food. Every year, taste and smell dysfunctions affect more than 200,000 people, including those undergoing…
Strengthening a patient’s immune functions to prevent infectious diseases without developing antibiotic resistance
Unmet Need Despite the development of numerous antibiotics over the years, the arms race between humans and emergent antibiotic-resistant microbes remains. More than 2.8 million antibiotic-resistant infections and 35,000 deaths occur in the U.S. each…
An algorithm for tracking nutrition that can accurately categorize foods based on image
Unmet Need Obesity prevalence for adults in the United States has reached 42.4% according to the most recent report from the National Center for Health Statistics. Given the public health and medical consequences of obesity…
A fluorescent probe for monitoring beta-secretase activity in cells
Molecular probes are provided for use in fluorescence microscopy procedures for monitoring beta-secretase enzyme (BACE) activity in living cells and organisms. The probes may be useful for monitoring Alzheimer's Disease-associated BACE in living cells. By…
Test of Verbal Expression and Reasoning (TOVER)
The TOVER is non-standardized assessment of expressive language in context and verbal reasoning. The 64 item test was specifically designed to assess language function in children and adults with Down syndrome across a broad range…