A peptide therapy for diabetes that improves islet cell mass and function

Methods of modulating blood glucose levels treating hyperglycemia and related complications and conditions by administration of a VGF biomolecule to a patient in need of such treatment are provided. Methods of enhancing insulin secretion from islet beta cells in a mammal exhibiting reduced insulin secretion by administration of a therapeutically effective amount of a VGF biomolecule are also provided.

Duke File (IDF) Number



  • Newgard, Christopher "Christopher"
  • Schisler, Jonathan
  • Stephens, Samuel

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School of Medicine (SOM)