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WireCleat – Fully safe Seldinger Technique device for prevention of guide wire retention
Unmet Need Catheters are widely used in many medical disciplines as a means of gaining easy access to internal body cavities like blood vessels or hollow organs. The Seldinger technique is a common method for…
Methods to modify plant stress responses and enhance expression of target proteins
Unmet Need There are over 8 billion people on our planet today that rely on several crops, including rice, corn, and wheat, as a primary source of sustenance. However, global climate change and the increased…
A humanized pro-N-cadherin antibody that can be used for treating and predicting heart failure
Unmet Need Heart failure is the leading cause of morbidity and mortality in the developed world. Approximately 50% of the US population over the age of 45 is expected to have preclinical heart failure, and…
A simple blood test that can predict heart failure earlier than current methods
Unmet Need Heart failure is the leading cause of morbidity and mortality in the developed world. Approximately 50% of the US population over the age of 45 is expected to have preclinical heart failure, and…
Data science and Python training modules for healthcare professionals
Unmet Need Data analytics and machine learning tools are becoming increasingly prevalent in healthcare settings, assisting in data organization, disease diagnosis, and treatment prediction. In North America alone, the machine learning market in the life…
Polymer dendrimers as potent and selective inhibitors of bacterial crop diseases
Unmet Need Currently, the agriculture industry relies on broad-spectrum antibiotics to ensure high crop yields, but farmers still suffer losses of 17-30% to disease and blight. Furthermore, the use of broad-spectrum antibiotics to treat these…
Methods for freeze-drying hydrogel microparticles
Unmet Need Biomaterial gels are appealing for several applications including tissue mimics, drug delivery, and regenerative medicine. Specifically, microporous annealed particle gels are porous biomaterial scaffolds comprised of spherical hydrogel based microparticles interconnected to form…
Combination cell and drug therapy for solid cancers
Unmet Need In 2022, there were 1.7 million estimated new solid cancer diagnoses and 500,000 estimated deaths. Existing chemo- and radiotherapies are not specific enough to the cancerous cells, causing debilitating off-target effects. New therapies…
Cell and animal models of pulmonary fibrosis
Unmet Need Pulmonary fibrosis is an irreversible and progressive disease characterized by the buildup of fibrotic material in the lungs, reducing lung function. There are over 200 different types of pulmonary fibrosis resulting from numerous…
Methods to utilize microbial organisms in the gut to modulate neurological responses
Unmet Need The gut is home to dynamic bacterial communities that shape the behavior of the host. The food we eat, our changes in mood, and even some of our social behaviors correlate with shifts…
High-stringency method for the isolation and proteomic identification of RNA binding proteins
Unmet Need RNA binding proteins (RBPs) play a critical role in maintaining stable gene expression, and they are involved in several related functions throughout eukaryotic cells, including splicing and translation. RBPs interact with RNA in…
Chemical modulators of immune checkpoints and cell growth for cancer treatment
Unmet Need Each year there are over 1.6 million new cases of cancer in the US, and over 600,000 cases prove fatal. Treating various types of cancer can be particularly challenging because of the complex…