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Showing 2 matches for the following: Inventor: "Stamler, Jonathan" ×
Avicins and thioesterification to control protein function
Value Proposition Thioesterification agents can modify cysteine groups of signaling proteins in order to modify their activity. Pathologies that could benefit from such protein modifications, which modulate physiologic redox status, include atherosclerosis, cancer, bacterial infections,…
Solid-Phase Alkyl Aryl Mixed Disulfides for Highly Efficient Cysteine/Thiol Immobilization
Technology The inventors have developed a strategy for purification of post-translationally modified peptides or proteins, and the identification of the various modifications. The methodology involves solid-phase immobilization of cysteine/thiol groups using mixed disulfides of resin-bound…