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Showing 8 matches for the following: Inventor: "Ramanujam, Nimmi" ×

Fiber optic probe with integrated photodetector capabilities

Fiber optic probe with integrated photodetector capabilities

Unmet Need Light-based diagnostics is a non-intrusive procedure that can be used to monitor chemotherapy treatment efficacy. Optical imaging additionally has the capacity for roles in diagnosis and surgery guidance. Currently, many devices for optic…

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A low-cost and effective ethanol ablation tumor treatment

A low-cost and effective ethanol ablation tumor treatment

Unmet Need Cervical cancer is the fourth most common cancer among woman globally, with an estimated 342,000 deaths in 2020, of which 90% of deaths occurred in low-and middle-income countries. A primary reason for this…

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Optical device for in vivo assessment of tissues

Optical device for in vivo assessment of tissues

Value Proposition Fluorescence and diffuse reflectance spectroscopy in the ultraviolet-visible (UV-VIS) spectrum are increasingly being investigated for tissue characterization. These biological scatterers, absorbers, and fluorophores may be used to indicate the existence of certain diseases.…

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A computational algorithm-based method for extracting intrinsic fluorescence properties of tissue

A computational algorithm-based method for extracting intrinsic fluorescence properties of tissue

Value Proposition Fluorescence spectroscopy has been used successfully to discriminate premalignancy and malignancy in a number of organ sites. However, due to the complex interplay of absorption, scattering, and fluorescence in tissue, it is difficult…

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Fiber optic probes with self-calibration capability for tissue optical spectroscopy

Fiber optic probes with self-calibration capability for tissue optical spectroscopy

Value Proposition UV-visible (UV-VIS) diffuse reflectance spectroscopy (DRS) is sensitive to the absorption and scattering properties of biological molecules in tissue and thus can be used as a noninvasive in vivo tool to obtain quantitative…

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A smart fiber optic sensor system for quantitative tissue optical spectroscopy

A smart fiber optic sensor system for quantitative tissue optical spectroscopy

Smart fiber optic sensors, systems, and methods for performing quantitative optical spectroscopy are disclosed. In one embodiment, smart fiber optic sensor can include a sensing channel, a calibration channel, and a pressure sensing channel. External…

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Optical assay system for intra operative assessment of tumor margins

Optical assay system for intra operative assessment of tumor margins

Researchers at Duke University have developed a new optical device that differentiates cancer from normal tissues by measuring tissue composition, and meets the intraoperative performance requirement that surgeons demand. The surgeon surveys the tumor surface…

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Optimization of fiber optic probes for spectroscopic measurements

Optimization of fiber optic probes for spectroscopic measurements

Value Proposition Early detection of cancer greatly increases the chances for a positive outcome. The World Health Organization states that there are two major components of early detection of cancer: increased awareness and screening. Diffuse…

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