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Showing 7 matches for the following: Inventor: "Ramanujam, Nimmi" ×
Rapid non-invasive optical assay system for intraoperative breast tumor margin assessment
Unmet Need Breast cancer is the most common non-skin cancer in women in the United States, accounting for 1 in 3 of all new female cancers each year. Breast conserving surgery is a common treatment…
Fiber optic probe with integrated photodetector capabilities
Unmet Need Light-based diagnostics is a non-intrusive procedure that can be used to monitor chemotherapy treatment efficacy. Optical imaging additionally has the capacity for roles in diagnosis and surgery guidance. Currently, many devices for optic…
Optical device for in vivo assessment of tissues
Value Proposition Fluorescence and diffuse reflectance spectroscopy in the ultraviolet-visible (UV-VIS) spectrum are increasingly being investigated for tissue characterization. These biological scatterers, absorbers, and fluorophores may be used to indicate the existence of certain diseases.…
A computational algorithm-based method for extracting intrinsic fluorescence properties of tissue
Value Proposition Fluorescence spectroscopy has been used successfully to discriminate premalignancy and malignancy in a number of organ sites. However, due to the complex interplay of absorption, scattering, and fluorescence in tissue, it is difficult…
Fiber optic probes with self-calibration capability for tissue optical spectroscopy
Value Proposition UV-visible (UV-VIS) diffuse reflectance spectroscopy (DRS) is sensitive to the absorption and scattering properties of biological molecules in tissue and thus can be used as a noninvasive in vivo tool to obtain quantitative…
A smart fiber optic sensor system for quantitative tissue optical spectroscopy
Smart fiber optic sensors, systems, and methods for performing quantitative optical spectroscopy are disclosed. In one embodiment, smart fiber optic sensor can include a sensing channel, a calibration channel, and a pressure sensing channel. External…
Optimization of fiber optic probes for spectroscopic measurements
Value Proposition Early detection of cancer greatly increases the chances for a positive outcome. The World Health Organization states that there are two major components of early detection of cancer: increased awareness and screening. Diffuse…