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Showing 5 matches for the following: Inventor: "Matsunami, Hiroaki" ×
New small molecules targeting castration-resistant prostate cancer
Unmet Need Prostate cancer (PC) is the second most common male cancer globally and represents 15% of all cancers diagnosed in males. An estimated 34,700 deaths were predicted to occur from PC in the U.S.…
Tools for the rational design of improved odorant ligands and receptors
Unmet Need Our sense of smell, or olfaction, is integral to myriad aspects of everyday life, from our health and safety to our personal preferences. Yet the mechanisms behind olfaction are not well understood, leading…
A system for screening compounds that alter smell perception
Unmet Need Olfactory sensation profoundly influences a person’s quality of life. In addition to the aesthetic aspects of life associated with olfactory sensation, approximately 2 million Americans experience some type of olfactory dysfunction. Studies show…
A method for identifying sour-taste receptor ligands as well as compounds that modulate their activity
Unmet Need The taste system is essential for feeding and survival as it helps humans evaluate the nutritional content in food. Every year, taste and smell dysfunctions affect more than 200,000 people, including those undergoing…
A platform for detecting and discriminating odorant molecules in the vapor phase
Unmet Need Mammals are capable of detecting and recognizing a large number of odors. Olfactory receptors (ORs) play a crucial role in detecting and recognizing odorant molecules. There has been growing interest in elucidating the…