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Showing 13 matches for the following: Inventor: "Grill, Warren" ×

Improved beta oscillation burst detection for assessment of Parkinson’s disease

Improved beta oscillation burst detection for assessment of Parkinson’s disease

Unmet Need Parkinson’s disease is a debilitating ailment, though therapies such as deep brain stimulation via electrodes can improve symptoms. Such therapies rely on feedback from biomarkers to adjust the stimulation parameters. Such biomarkers may…

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Systems and methods for efficient prediction and design of neural stimulation

Systems and methods for efficient prediction and design of neural stimulation

Unmet Need Bioelectronic therapy is the ability to deliver various electrical impulses to patients through implanted medical devices. These devices can treat heart failure, epilepsy, and chronic pain among other ailments. Depending on the disease,…

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Signals for onset-free conduction block

Signals for onset-free conduction block

Unmet Need Neuromodulation and neurostimulation devices are used to control the responses of the nervous system and alleviate disease. Delivering to a nerve an alternating current at a high frequency can produce a nerve block…

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A method for selectively blocking nerve fibers during neurostimulation treatment using kilohertz frequency electrical signals

A method for selectively blocking nerve fibers during neurostimulation treatment using kilohertz frequency electrical signals

Unmet Need In the past three decades implanted neurostimulation devices have become widely adopted driven largely by their ability to treat a range of clinical conditions with a “drug-free” solution. The $6.6 billion dollar market…

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An effective method for treating functional gastrointestinal and motility disorders using patterned electrical stimulation in the colon

An effective method for treating functional gastrointestinal and motility disorders using patterned electrical stimulation in the colon

Unmet Need Functional gastrointestinal and motility disorders (FGIMD) impact 1 in 5 persons in the U.S. It is a group of disorders classified by GI symptoms which include irritable bowel syndrome, fecal incontinence, constipation, and…

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A method to enable the use of a novel biomarker for deep brain stimulation treatments

A method to enable the use of a novel biomarker for deep brain stimulation treatments

Unmet Need Neuromodulation therapies are used to treat a wide variety of clinical conditions. For example, an estimated 150,000 deep brain stimulation (DBS) implants are performed globally to help treat movement disorders like Parkinson’s Disease.…

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A method to improve deep brain stimulation treatments by using cortical evoked potentials as a biomarker

A method to improve deep brain stimulation treatments by using cortical evoked potentials as a biomarker

Unmet Need Neuromodulation therapies are used to treat a wide variety of clinical conditions. For example, an estimated 150,000 deep brain stimulation (DBS) implants are performed globally to help treat movement disorders like Parkinson’s Disease.…

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Minimally invasive vagus nerve stimulation to improve cognitive function

Minimally invasive vagus nerve stimulation to improve cognitive function

Unmet Need Neuroinflammation is a major driver of cognitive deficits and the development of neurological disorders. The vagus nerve plays a critical role in regulating physiological responses to resolve neuroinflammation. Vagus nerve stimulation (VNS) is…

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Method to optimize spinal cord stimulation therapy placement and parameters

Method to optimize spinal cord stimulation therapy placement and parameters

Unmet Need Spinal cord stimulation (SCS) is an FDA approved therapy that stimulates the spinal cord using electrical pulses. This therapy is used to treat chronic pain, and it is estimated 50,000 spinal cord stimulating…

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A method to optimize neural activity blocking therapies

A method to optimize neural activity blocking therapies

Unmet Need The use of kilohertz frequency (KHF) as neuromodulatory therapies that block unwanted neural activity have been applied to treat chronic pain, phantom limb pain, obesity, and other applications. However, the high energy demands…

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A method to improve the clinical utility of kilohertz frequency alternating current devices to treat neurological disorders

A method to improve the clinical utility of kilohertz frequency alternating current devices to treat neurological disorders

Unmet Need Many neurological disorders, including pain and spasticity, are characterized by undesirable increases in sensory, motor, or autonomic nerve activity. Local application of kilohertz frequency alternating currents (KHFAC) can effectively and completely block the…

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An optimization method for spinal cord stimulation electrodes

An optimization method for spinal cord stimulation electrodes

Unmet Need Spinal cord stimulation is a trusted and proven treatment for patients with chronic pain, and spinal cord stimulator devices are implanted in 34,000 patients a year. Electrical stimulation is delivered via an implanted…

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