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Showing 4 matches for the following: Inventor: "Franz, Katherine" ×
Small molecules that can safely exploit copper as an antimicrobial
Value Proposition The fungal pathogen Cryptococcus neoformans can live in both plants and animals, but when inhaled by humans can disseminate from the lungs to the bloodstream and cause life-threatening systemic disease. The brain is…
A fluorescent probe for monitoring beta-secretase activity in cells
Unmet Need Alzheimer’s Disease (AD) is characterized by the accumulation of amyloid-beta (Aβ) plaques, which lead to neurotoxicity, synaptic damage, and neuronal cell death. Current therapeutic approaches face significant challenges due to the complex nature…
Prochelators as targeted prodrugs for prostate cancer
Value Proposition Globally, prostate cancer is the second-leading cause of new cancer cases in men and the sixth-leading cause of cancer-related death in men. Prostate-related health issues are on the rise, and the number of…
Antimicrobial prochelators to target drug-resistant bacteria
Value Proposition According to the CDC, each year 2.8 million people in the United States develop an antibiotic-resistant infection, leading to more than 35,000 deaths. Beta lactams were the largest segment in the antibiotics market…