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Showing 1 match for the following: Inventor: "Beaulieu, Martin" ×

Mice carrying functional single nucleotide polymorphisms in brain-specific trytophan hydroxylase(Tph2)

Mice carrying functional single nucleotide polymorphisms in brain-specific trytophan hydroxylase(Tph2)

We have developed mice expressing 2 different mutant alleles of the brain-specific tryptophan hydroxylase gene (Tph2). Tryptophan hydroxylase is the rate limiting enzyme involved in the synthesis of serotonin. These mice have significantly reduced levels…

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