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Small molecules

A drug combination that reduces weight gain associated with antidepressant therapy

Newer generation antidepressants seem less likely to be associated with...


Conjugated neuroactive steroid compositions and methods of use thereof

The present disclosure provides modified neuroactive steroids. The modified neuroactive...


A method of treating and preventing gastrointestinal disorders

Unmet Need Gastrointestinal disorders such as inflammatory bowel disease, constipation,...


Beta-arrestin inhibition to prevent S1P1 internalization as a treatment for intracranial diseases

Value Proposition Glioblastomas (GBMs) are among the most common and...


Diagnostic and treatment for chronic and acute phase myeloid leukemia

Value Proposition While cancer therapies have increased survival for many...


Treating heart failure with bisphosphonate compositions

Value Proposition The prevalence of heart failure (“HF”) has grown...


A process to selectively access allylic diamines that can aid in identifying new drug compounds

Unmet Need When developing new drugs, researchers often rely on...


Abl kinase inhibitors promote lung regeneration after pathogen and chemical-induced injury

Value Proposition Damage to the lung epithelium in response to...


C-nitroso donors of nitroxyl

Value proposition Heart failure is a chronic, progressive condition in...