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Small molecules

A drug combination that reduces weight gain associated with antidepressant therapy

Newer generation antidepressants seem less likely to be associated with...

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Conjugated neuroactive steroid compositions and methods of use thereof

The present disclosure provides modified neuroactive steroids. The modified neuroactive...

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A method of treating and preventing gastrointestinal disorders

Unmet Need Gastrointestinal disorders such as inflammatory bowel disease, constipation,...

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Beta-arrestin inhibition to prevent S1P1 internalization as a treatment for intracranial diseases

Value Proposition Glioblastomas (GBMs) are among the most common and...

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Diagnostic and treatment for chronic and acute phase myeloid leukemia

Value Proposition While cancer therapies have increased survival for many...

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Treating heart failure with bisphosphonate compositions

Value Proposition The prevalence of heart failure (“HF”) has grown...

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A process to selectively access allylic diamines that can aid in identifying new drug compounds

Unmet Need When developing new drugs, researchers often rely on...

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Abl kinase inhibitors promote lung regeneration after pathogen and chemical-induced injury

Value Proposition Damage to the lung epithelium in response to...

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C-nitroso donors of nitroxyl

Value proposition Heart failure is a chronic, progressive condition in...

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