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Shank3 knockout mice as a model for autism
The Shank3B- knockout allele has a neo cassette replacing the...
MORE >Mouse model of cholinergic dysfunction to evaluate cognitive enhancers for Alzheimer’s disease treatment
Value Proposition Defects in acetylcholine transmission have been associated with...
MORE >Genes involved in the pathogenesis of anxiety disorders including obsessive-compulsive disorder
Anxiety disorders are the most common mental illness in the...
MORE >The simultaneous assessment of multiple tumor driver genes using a cancer rainbow mouse
Value Proposition There is an ongoing effort to develop transformative...
MORE >Transgenic mice expressing mutant pig rhodopsin
Value Proposition ADRP (Autosomal Dominant Retinitis Pigmentosa) is a type...
MORE >A mouse strain lacking functional GRK4 gene
GRK4 is prominently expressed in testes, with expression also in...
MORE >Activated caspase-3 reporter mouse
The activated caspase-3 reporter mouse is an in vivo screening...
MORE >ZIP fish: zebrafish insulin promoter
Duke scientists have created stable transgenic zebrafish with strict pancreatic,...
MORE >Use of sustained-release 5-hydroxytrypophan in treating constipation
Unmet Need Over 10% of the population suffers from constipation...
MORE >Enclosure device to track fine-scale movements of animals in 3D with a single camera
Unmet Need A major component of medical research and preclinical...
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