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A method to enable the use of a novel biomarker for deep brain stimulation treatments
Unmet Need Neuromodulation therapies are used to treat a wide variety of clinical conditions. For example, an estimated 150,000 deep brain stimulation (DBS) implants are performed globally to help treat movement disorders like Parkinson’s Disease.…
A new therapeutic target for preventing hair loss in chemotherapy-treated cancer patients
Unmet Need Losing one’s hair is a profoundly unnerving phenomenon that affects daily life, social relationships, and even one’s own confidence. While about 2% of the world’s population suffers from general hair loss, it is…
Methods and compositions for treating protein aggregation diseases
Unmet Need Neurodegenerative disease affects more than 50 million people per year. Certain neurodegenerative diseases, like Alzheimer’s disease, result from the accumulation of amyloid-forming proteins in the brain, which results in cognitive impairment and has…
Bioresorbable lactone-based elastomers that can be used in continuous digital light processing 3D printing applications
Unmet Need The global market for 3D printing, or additive manufacturing, is growing rapidly with a compound annual growth rate of approximately 21% predicted to occur until 2027. Medical and dental products account for the…
A method to improve deep brain stimulation treatments by using cortical evoked potentials as a biomarker
Unmet Need Neuromodulation therapies are used to treat a wide variety of clinical conditions. For example, an estimated 150,000 deep brain stimulation (DBS) implants are performed globally to help treat movement disorders like Parkinson’s Disease.…
Methods to utilize microbial organisms in the gut to modulate neurological responses
Unmet Need The gut is home to dynamic bacterial communities that shape the behavior of the host. The food we eat, our changes in mood, and even some of our social behaviors correlate with shifts…
A multi-electrode multiplexed channel brain-computer interface for patient assistive technologies
Unmet Need According to the WHO, in 2019 neurological disorders were recognized as a growing public health challenge resulting in over 500,000 deaths globally. In the US alone, neurological diseases cause an estimated $800 billion-dollar…
Portable mass spectrometer with high sensitivity and resolution
Unmet Need Mass spectrometry is a method of particle composition analysis. Traditionally, mass spectrometers are large devices with high energy requirements, restricting them to high-resource laboratory settings. Mass spectrometry can be used for isotopic analysis…
Breast cancer risk prediction technology using genomic classifier
Unmet Need The earliest form of breast cancer, ductal carcinoma in situ (DCIS), is diagnosed in almost 50,000 people in the U.S. each year. DCIS is considered noninvasive, as abnormal cells have not spread out…
An antiviral polymer that enables nasal spray to protect against COVID
Unmet Need Despite the availability of effective intramuscular vaccines, COVID continues to spread around the globe. Intramuscular shots do a good job of reducing disease severity and preventing hospitalization, but they are difficult to ship,…
A nanoparticle-based material to improve water purification processes
Unmet Need Water is one of our most precious and essential commodities. It is no surprise that the United Nations recognized access to clean drinking water as an essential component to the realization of all…