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Targeting novel cytokine receptors for anti-cancer activity on human cancers

Targeting novel cytokine receptors for anti-cancer activity on human cancers

Researchers at Duke University have discovered novel mRNA isoforms of a cytokine receptor that are expressed in a variety of cancers, including breast and cervical cancer cells. They have created cell lines expressing these abnormal…

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Miniaturized, ultra-high density, multichannel electrode array for long-term, intra-cranial neuronal recordings

Miniaturized, ultra-high density, multichannel electrode array for long-term, intra-cranial neuronal recordings

Technology A high-density multichannel microwire electrode array is disclosed. The array can comprise a variable number of electrodes. A method of assembling the array is further disclosed. Additionally, a plurality of devices employing the array…

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Pulse duration and the dynamics of infrared tissue ablation

Pulse duration and the dynamics of infrared tissue ablation

Value Proposition Laser-based ablation procedures are being investigated as a minimally invasive form of surgery to treat several forms of cancerous as well as non-cancerous lesions in neuro-, ophthalmic-, and cardiothoracic-surgery. While several different types…

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Two dimensional electrophoresis cassette

Two dimensional electrophoresis cassette

A device for two-dimensional electrophoresis includes a cassette comprising two opposing plates. The two opposing plates form a first elongated portion for receiving a first elongated electrophoretic separation medium and a second portion extending away…

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A diagnostic test for differentiating follicular thyroid adenoma for follicular thyroid carcinoma

A diagnostic test for differentiating follicular thyroid adenoma for follicular thyroid carcinoma

Duke University is seeking a company interested in commercializing a novel method to distinguish follicular thyroid adenoma (FTA) from follicular thyroid carcinoma (FTC). Global estimates of thyroid cancer incidence for 2006 indicate half a million…

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A gene implicated in the causation of kidney disease

A gene implicated in the causation of kidney disease

Duke University is seeking a company interested in commercializing a risk assessment test and/or a therapeutic product targeting a gene which has been implicated in Glomerulonephritis. Focal and segmental glomeruloschlerosis (FSGS) is a significant cause…

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Spike detection and data compression for a brain machine interface

Spike detection and data compression for a brain machine interface

Technology Systems, Methods, and Computer Program Products for Transmitting Neural Signal Information. Systems, method, and computer program products are provided for neural signal transmission. A system according to one embodiment can include a signal receiver…

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APOE polymorphisms associated with SEPSIS risk

APOE polymorphisms associated with SEPSIS risk

Duke University is seeking a company interested in commercializing a novel and versatile diagnostic/prognostic methodology which teaches identifying a patient who will have a post operative reduced risk of sepsis based on the pre-op detection…

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Stem cell-derived factors for treating pathologic conditions

Stem cell-derived factors for treating pathologic conditions

1.3 million Americans experience a heart attack (acute myocardial infarction or AMI) each year. A significant percentage of these patients die from restricted blood flow to the heart (ischemia) and significant loss of cardiac function.…

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BANJO: Software and algorithms for the efficient and flexible inference of Bayesian and dynamic Bayesian networks

BANJO: Software and algorithms for the efficient and flexible inference of Bayesian and dynamic Bayesian networks

Duke University is seeking a company interested in commercializing a novel and versatile software. BANJO is software for the efficient and flexible inference of Bayesian and dynamic Bayesian networks. The target of the Banjo tool…

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Optical assay system for intra operative assessment of tumor margins

Optical assay system for intra operative assessment of tumor margins

Researchers at Duke University have developed a new optical device that differentiates cancer from normal tissues by measuring tissue composition, and meets the intraoperative performance requirement that surgeons demand. The surgeon surveys the tumor surface…

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Black blood delayed enhancement magnetic resonance imaging

Black blood delayed enhancement magnetic resonance imaging

Technnology Duke University is seeking a corporate partners to commercialize a method of improved detection of infarcted heart tissue. The technology provides a dark blood delayed enhancement technique that improves the visualization of subendocardial infarcts…

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