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BANJO: Software and algorithms for the efficient and flexible inference of Bayesian and dynamic Bayesian networks
Duke University is seeking a company interested in commercializing a novel and versatile software. BANJO is software for the efficient and flexible inference of Bayesian and dynamic Bayesian networks. The target of the Banjo tool…
Optical assay system for intra operative assessment of tumor margins
Researchers at Duke University have developed a new optical device that differentiates cancer from normal tissues by measuring tissue composition, and meets the intraoperative performance requirement that surgeons demand. The surgeon surveys the tumor surface…
Black blood delayed enhancement magnetic resonance imaging
Technnology Duke University is seeking a corporate partners to commercialize a method of improved detection of infarcted heart tissue. The technology provides a dark blood delayed enhancement technique that improves the visualization of subendocardial infarcts…
C-nitroso donors of neutral nitric oxide to treat hypertension and other diseases
Value proposition Hypertension, also known as high blood pressure, can lead to severe complications and increase the risk of heart disease, stroke, and death. About 1 out of 3 US adults, or about 75 million…
Acoustic lens for shockwave lithotripsy
Systems and methods for providing therapeutic shock waves are provided. A modified acoustic lens can include a first lens portion for directing a first part of an acoustic shock wave pulse toward a target and…
Composition and methods of multi-targeted siRNA cocktail for treatment of Glioblastoma Multiforme
Value Proposition Glioblastoma is the most common primary malignant brain tumor in adults, and the prognosis of this disease is dismal, despite aggressive standard-of-care therapy with chemoradiation and gross tumor resection. Several molecular mechanisms are…
Tunable metamaterial
Technology Metamaterial comprising a plurality of resonators disposed on a substrate, the substrate comprising a dielectric support layer and a relatively thin semiconductor layer, having a Schottky junction between at least one conducting resonator and…
Automated segmentation of layered structures such as retinal layers using graph cuts
Disclosed herein are systems and method for segmentation and identification of structured features in images. According to an aspect, a method may include representing an image as a graph of nodes connected together by edges.…
XCAT phantom CT projector
The XCAT, MOBY, and ROBY phantoms include a great amount of anatomical detail that make them suitable for use in high-resolution CT imaging research. To simulate CT imaging process, we developed a CT projector that…
Conjugated neuroactive steroid compositions and methods of use thereof
The present disclosure provides modified neuroactive steroids. The modified neuroactive steroids may comprise, consist of, or consist essentially of a therapeutic agent and/or a modifying moiety. The modified neuroactive steroid can have modified characteristics as…
Detailed brain model for imaging research
The XCAT brain phantom program includes a highly detailed anatomy for the human brain. Over 100 structures and vessels are modeled based on MRI data. The program will generate voxelized versions of the brain at…
XCAT library of anatomical models for CT imaging research
In addition to the standard male and female adult anatomies of the XCAT, we also developed several other models based on CT imaging data. Each model includes the same amount of detail as the original…