Skip to main content
Feature-free photogrammetric 3D imaging with cameras under unconstrained motion

Feature-free photogrammetric 3D imaging with cameras under unconstrained motion

Unmet Need With the increasing development of camera-based sensors for applications such as virtual and augmented reality, there is more demand for technologies that can image 3D structures and create interpretable digital representations – a…

Read More

Acoustofluidic technologies for precision control in microfluidic systems

Acoustofluidic technologies for precision control in microfluidic systems

Unmet Need Achieving precise manipulation of particles, cells, and droplets in microscale liquid systems is a major challenge in life sciences, material sciences, and chemistry. Traditional microfluidic systems, which use hydrophobic channels and pressure differentials…

Read More

Mask embedding for realistic high-resolution image synthesis

Mask embedding for realistic high-resolution image synthesis

Unmet Need General adversarial networks (GANs) are machine learning networks made of two neural networks competing with each other. They are used in medical imaging to generate training datasets for various medical imaging diagnostic processing…

Read More

An automated system for dermatological laser surgery

An automated system for dermatological laser surgery

Value Proposition Laser-based devices show promise for highly effective treatment of a range of cutaneous applications, including skin rejuvenation, tattoo removal, hair removal, vascular and pigmented lesions, and even skin cancers. During these procedures, a…

Read More

Targeted delivery of gene therapy via exosomes for cardiomyocyte reprogramming

Targeted delivery of gene therapy via exosomes for cardiomyocyte reprogramming

Unmet Need Every year, close to 1 million Americans experience a heart attack. A heart attack results in the loss of specialized cells called cardiomyocytes, which are crucial for the heart’s contraction and rhythmic beating.…

Read More

FK506/FK520 analogs modified to increase fungal specificity and reduce immunosuppression

FK506/FK520 analogs modified to increase fungal specificity and reduce immunosuppression

Unmet Need Fungal infections are becoming increasingly prevalent worldwide, with 150 million cases and 1.7 million fatalities reported in the last year alone. The challenge in treating these infections stems from the rise of multi-drug-resistant…

Read More

Novel RNA-based anti-cancer therapeutic for sustained immunotherapy by combined pattern recognition receptor (PRR) activation and anti-microRNA therapy (AMT)

Novel RNA-based anti-cancer therapeutic for sustained immunotherapy by combined pattern recognition receptor (PRR) activation and anti-microRNA therapy (AMT)

Unmet Need Cancer is incredibly prevalent and current therapies are insufficient. Globally, lifetime prevalence is 1 in 5, and mortality is 1 in 9 in men and 1 in 12 in women. Solid tumors account…

Read More

HIV treatment and prevention using broadly neutralizing antibodies

HIV treatment and prevention using broadly neutralizing antibodies

Unmet Need For over 40 years, the HIV pandemic has affected millions, reducing life expectancy and quality of life. As of 2021, 38.4 million people globally are living with HIV, with about 1.5 million new…

Read More

Novel epigenome editors for multiplexed gene regulation

Novel epigenome editors for multiplexed gene regulation

Unmet Need Epigenome editors activate or inhibit gene expression without modifying the underlying DNA sequence. Consequently, these editors can reversibly fine-tune gene expression without the risk of permanently altering the genome or off-target editing. Epigenome…

Read More

Splice switching oligonucleotides to restore PHKG2 expression in glycogen storage disease IX

Splice switching oligonucleotides to restore PHKG2 expression in glycogen storage disease IX

Unmet Need Glycogen Storage Disease IX (GSD IX) is a rare inherited disorder primarily caused by mutations in the PHKG2 gene, leading to significant deficiencies in glycogen metabolism. Patients typically present with a variety of…

Read More

Methods of treatment in diseases treated with therapeutic proteins

Methods of treatment in diseases treated with therapeutic proteins

Unmet Need The challenge of antibody formation against protein replacement therapies (PRT) significantly impacts the efficacy of treatments as patients often develop anti-drug antibodies, particularly those who are CRIM-negative, leading to adverse outcomes and limiting…

Read More

A fluorescent probe for monitoring beta-secretase activity in cells

A fluorescent probe for monitoring beta-secretase activity in cells

Unmet Need Alzheimer’s Disease (AD) is characterized by the accumulation of amyloid-beta (Aβ) plaques, which lead to neurotoxicity, synaptic damage, and neuronal cell death. Current therapeutic approaches face significant challenges due to the complex nature…

Read More

Have Questions?

Please contact us or subscribe for more opportunities

Stay in Touch with Us