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At-home monitoring and alert system for infant blood oxygen levels and heart rate
Unmet Need Every year there are over 1,000 babies born in the US with a congenital heart disease known as hypoplastic left heart syndrome (HLHS). HLHS affects the structure of the left side of the…
A method to increase the durability and lifespan of commercially available soft polymer networks
Unmet Need Soft polymers are used for a variety of products including biomedical implants, footwear, and tires. Having a more durable polymer product will increase not only the lifespan of the product but also the…
Drone and data capture system that measures biodiversity in remote, dense environments
Unmet Need Biodiversity and ecosystems writ large are of tremendous importance to conservation science and ecology, as well as human health, security, and economic growth. However, human encroachment on habitat continues to increase while at…
Augmented Reality for Neurosurgery
Unmet Need Approximately 30% of the 3.5 million epilepsy patients in the United States struggle to control seizures despite receiving existing treatments. These patients often undergo neurosurgery to help alleviate their symptoms. Surgical planning involves…
A process to access selectively 1,4-diamines with two stereogenic centers that can aid in identifying new drug compounds
Unmet Need When developing new drugs, researchers often rely on naturally occurring compounds to learn what design features illicit a biological response that can be tailored for treating a given disease or ailment. However, reproducing…
A process to access selectively 1,4-diamines with two stereogenic centers that can aid in identifying new drug compounds
Unmet Need When developing new drugs, researchers often rely on naturally occurring compounds to learn what design features illicit a biological response that can be tailored for treating a given disease or ailment. However, reproducing…
Novel epigenome editors for multiplexed gene regulation
Unmet Need Epigenome editors activate or inhibit gene expression without modifying the underlying DNA sequence. Consequently, these editors can reversibly fine-tune gene expression without the risk of permanently altering the genome or off-target editing. Epigenome…
Torque Assisting Device for Endoscopy
Unmet Need Colorectal cancer is the third leading cause of cancer-related deaths in the United States. As a preventative measure, more than 15 million colonoscopies are performed in the United States each year. This common…
Intravesical UTI vaccine to induce bacteria-eradicating immune responses in the bladder
Unmet Need Urinary tract infections (UTI) are typically caused by uropathogenic E. coli (UPEC) that proliferate in urine and infect the urethra and bladder epithelial cells. UTIs represent the second most common bacterial infection in…
Transcatheter device for restricting blood flow through the pulmonary artery
Unmet Need In the United States, approximately 10,000 newborns a year will require surgery for a congenital heart defect such as atrial or ventricular septal defects. These defects can cause excessive blood flow to the…
Data collection system for surgical instrument localization
Unmet Need There is no data that describes how surgical instruments are used in open surgery – the vast majority of operations. Achieving accurate intraoperative instrument position data could help improve surgical approaches and accreditation,…
A smartphone-based detector for mobile health applications
Unmet Need It is estimated that there are over 6 billion smartphone users worldwide, which translates to almost 83% of the world’s population. Due to their widespread use, smartphones present a golden opportunity to redefine…