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Data collection system for surgical instrument localization

Data collection system for surgical instrument localization

Unmet Need There is no data that describes how surgical instruments are used in open surgery – the vast majority of operations. Achieving accurate intraoperative instrument position data could help improve surgical approaches and accreditation,…

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A smartphone-based detector for mobile health applications

A smartphone-based detector for mobile health applications

Unmet Need It is estimated that there are over 6 billion smartphone users worldwide, which translates to almost 83% of the world’s population. Due to their widespread use, smartphones present a golden opportunity to redefine…

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Rapid detection of diagnostic TERT promoter mutations in glioblastoma and other cancers

Rapid detection of diagnostic TERT promoter mutations in glioblastoma and other cancers

Unmet Need Malignant gliomas are the most common primary central nervous system (CNS) malignancy in adults and are graded I to IV indicating their degree of malignancy. Diffuse gliomas (grade II-IV) account for 80% of…

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Rapid detection of diagnostic TERT promoter mutations in glioblastoma and other cancers

Rapid detection of diagnostic TERT promoter mutations in glioblastoma and other cancers

Unmet Need Malignant gliomas are the most common primary central nervous system (CNS) malignancy in adults and are graded I to IV indicating their degree of malignancy. Diffuse gliomas (grade II-IV) account for 80% of…

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Surgical device to insert graft between skull and dura

Surgical device to insert graft between skull and dura

Unmet Need About 16,000 patients per year are diagnosed with a mastoid space defect. This is a defect in the skull that leads to hearing loss caused by cerebrospinal fluid leaking into the mastoid space,…

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High-speed 3D tomographic imaging using a camera array

High-speed 3D tomographic imaging using a camera array

Unmet Need Tomographic imaging has revolutionized both scientific research and clinical procedures. 3D tomographic imaging reveals information about a sample’s volume, depth, and internal structures, which cannot be obtained from 2D imaging alone. However, 3D…

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A synergistic chemotherapy and radiotherapy drug delivery technology for treating prostate cancer tumors

A synergistic chemotherapy and radiotherapy drug delivery technology for treating prostate cancer tumors

Unmet Need Pancreatic cancer is one of the deadliest manifestations of cancer in clinical oncology. Despite accounting for only 3.2% of all cancer cases, it is the third leading cause of cancer-related mortality. National Comprehensive…

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Gene signature-based screening tool for Castration Resistant Prostate Cancer

Gene signature-based screening tool for Castration Resistant Prostate Cancer

Unmet Need Prostate cancer is the second most common type of cancer diagnosed among adult males, with the first line of treatment being androgen deprivation therapy (ADT). However, up to 20% of patients develop a…

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Blood pressure control by gene editing

Blood pressure control by gene editing

Unmet Need The World Health Organization estimates that high blood pressure (hypertension) results in approximately 9 million annual deaths worldwide. Currently available drugs used to control blood pressure can be effective but are limited by…

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Method for rapid regeneration of modifiable stable cell lines

Method for rapid regeneration of modifiable stable cell lines

Unmet Need Characterizing the composition and function of protein complexes can facilitate the understanding of key cellular processes. Indeed, the global proteomics market was estimated to be USD 25.9 billion in 2021. However, the analysis…

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At-home acute hospital care guidebook

At-home acute hospital care guidebook

Unmet Need Over the last 40 years, the number of hospitals and hospital beds in the U.S. has declined, while the demand for emergency department services has increased. As a result, a reported 90% of…

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Reducing emergency department crowding through machine learning technology

Reducing emergency department crowding through machine learning technology

Unmet Need Over the last 40 years, the number of hospitals and hospital beds in the U.S. has declined, while the demand for emergency department services has increased. As a result, emergency department crowding has…

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