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Method and system for evaluating stability of cardic propagation reserve
Unmet Need About 325,000 people in the United States die from sudden cardiac death (SCD) caused by ventricular tachyarrhythmias (VT) each year. When a patient experiences VT, the lower chamber of their heart beats faster…
Transcriptional alterations during blood storage to monitor stored red cells and reduce storage-lesions
Unmet Need Currently, red blood cell (RBC) testing focuses on factors such as hemoglobin content, RBC count, blood typing, and antibody content. These tests, though comprehensive, do not measure the health and quality of RBCs.…
ECG rhythm database
Invention Summary Duke inventors have developed a database of digital 12- lead ECG samples that represent key rhythms of cardiac disorders. Each patient’s disorder was validated by a licensed and board-certified cardiovascular medicine physician to…
Data quality assurance framework for machine learning in healthcare
Unmet Need Currently, larger clinical datasets and electronic health records are fraught with unstandardized parameters and invalid datapoints that can cascade in downstream analyses. Such errors have a 92% incidence rate. These errors would be…
Multiscale coherence imaging for assessing epithelial tissue health in precancerous detection
Unmet Need Epithelial cells act as the body’s first line of defense against foreign elements and are constantly being replaced by newly grown cells. Due in part to these factors, 90% of all cancers originate…
Surgical needle for real-time electromagnetic navigation in trigeminal rhizotomy
Unmet Need Trigeminal neuralgia (TN) is a debilitating disorder that involves severe and recurring facial pain caused by irritation of the trigeminal nerve. Percutaneous trigeminal rhizotomy (PTR) is a preferred treatment for TN because it…
Sensor system to accurately measure head dynamics and kinematics
Unmet Need It is estimated that over 1.2 million individuals working in the United States have vibration syndrome due to long-term exposure to tools or machinery. This can lead to blood vessel and nerve damage,…
A highly sensitive next-generation sequencing technique for detecting cancerous mutations
Unmet Need Next-generation sequencing (NGS) methods have been widely adopted for both biological discovery and diagnostics in cancer patient care. In particular, the identification of new mutations or groups thereof arising within oncogenic pathways across…
A plate assay for in situ imaging of microbial growth in biofilms
Unmet Need As the study of antimicrobial-resistant biofilms becomes increasingly relevant, there is a need for a microplate assay that allows for continuous monitoring of biofilm formation by confocal laser scanning microscopy (CLSM). Microplate assays…
An eLearning platform with comprehensive engagement analytics and curated content to advance surgical education
Unmet Need As medicine continues to evolve and complexify while academic faculty face growing time constraints, self-study tools like online learning (eLearning) become invaluable for bridging the gap in medical trainee education. In particular, eLearning…
The Delirium Care Process Model: An interactive flowchart to standardize and inform delirium diagnosis and care
Unmet Need In the United States, the geriatric population was estimated to be about 55.8 million in 2020, comprising 17% of the total population. The size of this population is only expected to increase as…
The Fit Together Playbook: a curriculum that fosters community partnerships to fight child obesity
Unmet Need Childhood obesity affects 1 in 5 children resulting in more than 14.7 million obese children ages 2-19 years old in the United States. Many factors can contribute and cause obesity including diet, lack…