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Construction of patient specific 3D hemodynamic models through 2D angiograms for diagnosis and prognosis of atherosclerosis
Value Proposition Atherosclerotic Cardiovascular Disease is the leading cause of death globally. By some accounts, it claims as many as 17.3 million lives every year. Current diagnostic tests such as CT Angiography and Coronary angiography…
Multicompartment interventional wire and catheter storage basin
Value Proposition Catheters are hollow tube-like medical devices that can be inserted into blood vessels, ducts or body cavities. Catheters are ubiquitously used for the drainage of fluids, the infusion of fluids or the insertion…
Arbitrary viewpoint robotic manipulation
Value Proposition Real-time 3D imaging via tools such as OCT, 3D Ultrasound, and fast MRI/CT allow a surgeon to view the subject of interest from multiple perspectives, including those that are otherwise physically impossible. The…
Shank3 knockout mice as a model for autism
The Shank3B- knockout allele has a neo cassette replacing the PDZ domain (exons 13-16) of the Shank3 gene, resulting altered expression of the Shank3b isoform. These mice may be useful for studying behavioral abnormalities associated…
Providing surface contrast in rendering of three-dimensional images for micro-surgical applications
Value Proposition Recent advancements in optical coherence tomography (OCT) technology have greatly improved image quality and have facilitated the acquisition, processing, and display of three-dimensional information in real-time. As a result, this technology can now…
Mast cell targeting to predict and prevent virus-induced vascular leakage
Value Proposition Dengue is a mosquito spread virus that affects millions of people worldwide. According to the World Health Organization, there are approximately 390 million dengue virus infections each year, and it is the leading…
Electro-stimulation device to promote bladder voiding
Value Proposition Despite its association with a diverse array of conditions and particularly high prevalence among the elderly, underactive bladder lacks reliable clinical treatment options. Many pharmacological treatments have proven ineffective and cause undesirable side…
Long working distance optical coherence tomography system
Value Proposition Optical coherence tomography (OCT) has become the standard of care for diagnosis of many retinal pathologies. However, current commercial OCT systems require a skilled technician/photographer and cooperative subjects to obtain and maintain subject…
A method and apparatus for the onsite treatment and disinfection of concentrated blackwater
Value Proposition Over two billion people globally do not have access to safe, affordable sanitation, with many living in parts of the developing world that lack the required infrastructure to provide centralized water purification. The…
Compositions and methods for treating gram-negative bacterial infection
Value Proposition Antimicrobial resistance is considered to be one of the biggest crises facing modern medicine today. Without desperately needed intervention, it is estimated that by 2050 over 10 million deaths per year will be…
Bacteria interaction sorter
Value Proposition Microbe-microbe interactions influence microbial community dynamics, composition, and impact on the host. Thus, uncovering these interactions will enhance our scientific understanding of microbial communities and help aid efforts to manipulate bacterial communities which…