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Providing surface contrast in rendering of three-dimensional images for micro-surgical applications
Value Proposition Recent advancements in optical coherence tomography (OCT) technology have greatly improved image quality and have facilitated the acquisition, processing, and display of three-dimensional information in real-time. As a result, this technology can now…
Mast cell targeting to predict and prevent virus-induced vascular leakage
Value Proposition Dengue is a mosquito spread virus that affects millions of people worldwide. According to the World Health Organization, there are approximately 390 million dengue virus infections each year, and it is the leading…
Electro-stimulation device to promote bladder voiding
Value Proposition Despite its association with a diverse array of conditions and particularly high prevalence among the elderly, underactive bladder lacks reliable clinical treatment options. Many pharmacological treatments have proven ineffective and cause undesirable side…
Long working distance optical coherence tomography system
Value Proposition Optical coherence tomography (OCT) has become the standard of care for diagnosis of many retinal pathologies. However, current commercial OCT systems require a skilled technician/photographer and cooperative subjects to obtain and maintain subject…
A method and apparatus for the onsite treatment and disinfection of concentrated blackwater
Value Proposition Over two billion people globally do not have access to safe, affordable sanitation, with many living in parts of the developing world that lack the required infrastructure to provide centralized water purification. The…
Compositions and methods for treating gram-negative bacterial infection
Value Proposition Antimicrobial resistance is considered to be one of the biggest crises facing modern medicine today. Without desperately needed intervention, it is estimated that by 2050 over 10 million deaths per year will be…
Bacteria interaction sorter
Value Proposition Microbe-microbe interactions influence microbial community dynamics, composition, and impact on the host. Thus, uncovering these interactions will enhance our scientific understanding of microbial communities and help aid efforts to manipulate bacterial communities which…
An integrated hybrid biological-materials platform for portable production of biomacromolecules
Value Proposition Bacteria are a common host to produce diverse biologics, accounting for ~30% of biopharmaceuticals. The industrial synthesis of recombinant proteins using bacterial hosts entails multiple steps that each require a sophisticated and delicate…
Novel AnnexinA1 tripeptide (ANXA1sp) improves acute kidney injury after deep hypothermic circulatory arrest
Value Proposition Heart disease is the leading cause of death in industrialized nations across the world, with treatments often requiring surgery such as coronary artery bypass graft (CABG) or even transplantation. Although cardiac surgery is…
Isolated organ viral, theraputic or cell therapy delivery
Value proposition Cardiovascular diseases (CVD) remain the leading cause of death worldwide. The number of CVD patients with heart failure (HF) in the US is approaching 6.5 million adults and is estimated to increase by…
Induction of immunogenic cell death in cancer cells using modified ssRNAs
Value proposition Cancer immunotherapy is showing great promise against numerous cancer types in clinical trials. Consequently, this market is projected to rapidly grow to over $200 billion by 2021. Among the list of effective immunotherapies…