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Evecxia Therapeutics Reports Favorable Data From a Phase 1 Single Ascending Dose Safety/Tolerability/PK/PD Trial of EVX-301

Evecxia Therapeutics is a Duke University start-up, founded by inventors Drs. Jacob Jacobsen and Marc Caron (Cell Biology, SOM) around their serotonin synthesis amplification therapeutic technology for mental health applications.

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Isolere Bio: Inside the journey of a Duke biotech start-up

From an invention in 1999, to start-up creation in 2017, to acquisition in 2023, learn of the twists and turns of Duke start-up Isolere Bio from its co-founders.

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Four Points Innovation Funds Research Collaboration Between Duke University and The University of Manchester

This investment aims to accelerate research to develop a novel therapy to treat a genetic condition called Alport syndrome.

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Donaldson Acquires Isolere Bio, Continuing to Build Life Sciences Business

“Isolere is thrilled to join the Donaldson family and bring our novel affinity-phase separation technology to market,” said Kelli Luginbuhl, Ph.D, co-founder and chief executive officer of Isolere.

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Xilis and MD Anderson Announce Strategic Collaboration to Advance Novel Technology and Accelerate Therapeutic Development

Preclinical research agreement brings together Duke start-up Xilis' MicroOrganoSphere™ platform with MD Anderson's expertise in cancer research and therapeutic development.

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Sparta Biomedical, Dr. Wiley highlighted by WXII 12 News

Professor of Chemistry Dr. Benjamin Wiley was interviewed recently by Winston-Salem TV station WXII 12 News about the synthetic cartilage his lab developed.

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Duke’s Aravind Asokan, Ph.D., named Global Scholar

As a Novartis Institute for Biomedical Research (NIBR) Global Scholar, Asokan will receive up to $1 million in funding over three years, along with "drug-hunting expertise from dedicated NIBR scientific collaborators" as part of this…

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Istari Oncology Announces First Patient Dosed in the Non-Muscle-Invasive Bladder Cancer (NMIBC) Substudy of the LUMINOS-103 Basket Trial Evaluating Lerapolturev Monotherapy

Istari Oncology was founded by Drs. Darell Bigner and Matthias Gromeier (Neurosurgery, SOM).

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FDA approves elacestrant for ER-positive, HER2-negative, ESR1-mutated advanced or metastatic breast cancer

Radius Health, with its eventual partner Stemline Therapeutics/Menarini Group, licensed the cancer indications for this drug in 2017 out of the lab of Dr. Donald McDonnell (Pharmacology and Cancer Biology, SOM).

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